But there are actually two drawbacks to uv sterilization against bacteria:

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One is that ultraviolet light has an effect not only on bacteria, but also on mammalian cells.The second is that bacterial spores are highly resistant to ultraviolet light, which is somewhat worrying.The dormant spores of bacillus subtilis, for example, are five to 50 times more resistant to ultraviolet radiation than the corresponding growing cells.

Spore photoproduct lyase (spore photoproduct lyase) is a unique DNA repair enzyme that makes spores so resistant.During endospore germination, SP lyase can repair DNA damage induced by ultraviolet radiation.Bacterial spores are highly resistant to physical damage such as heat, ionization, ultraviolet and gamma radiation, osmotic pressure, and dryness.Spores also protect bacteria from chemical and biological disinfectants such as iodine, peroxides, and alkylating agents.So even crude physical and chemical methods can't get rid of bacterial spores.The so-called wildfire burn, the spring breeze is born.Therefore, it is urgent to develop other more effective sterilization methods.